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Phase I human trial of parent molecule (TB-4) showed no serious adverse events Mild injection site reactions possible Same theoretical angiogenesis/tumor concern as BPC-157 Head rush or lightheadedness reported anecdotally at higher doses Can You Stack BPC-157 and TB-500

That is why it is used in both nerve conditions and B12-related anemia

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For example, the sensitization of TRPA1 with a low dose exposure to acrolein causes sensitization of TRPV1 against capsaicin.[ref] Studies in workplaces that have high VOC levels show that TRPA1 activation is the molecular initial event (MIE) leading to sensory irritation.[ref] A 2022 study investigated the sensitivity to capsaicin, a TRPV1 receptor activator, in people with MCS compared to a control group