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average body-weight loss with semaglutide STEP-1 trial (NEJM) average body-weight loss with tirzepatide SURMOUNT-1 trial (NEJM) lower risk of major heart events SELECT trial (NEJM) Figures are from peer-reviewed clinical trials of the active ingredients (semaglutide and tirzepatide), not a guarantee of individual results

doi: 10.1146/annurev.nutr.012809.104755 239