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If you have symptoms like fatigue, brain fog, or nerve pain plus suboptimal B12 levels, a trial of supplementation is worth trying since it's very safe
Multiple mechanisms may interrelate NNMTi treatment with the microbiome
1 Asymptomatic autoimmune gastritis likely precedes gastric atrophy by 10 to 20 years, followed by the onset of iron-deficiency anemia that occurs as early as 20 years before vitamin B 12 deficiency pernicious anemia
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