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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for several indications: type 2 diabetes mellitus, chronic weight management, and more recently, to reduce the risk of major adverse cardiovascular events in adults with established cardiovascular disease and either overweight or obesity
In December 2024, Zepbound received an additional indication for treating adults with OSA and obesity and is the first pharmaceutical treatment for OSA
A clinical review in the New England Journal of Medicine reported clear differences in metabolic effects between these drugs, which may change the intensity of symptoms
it improves our muscle-to-fat ratio, which helps us stay active and independent in daily tasks as we get older
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