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In patients with renal dysfunction, refractory hypotension, severe metabolic abnormalities, active seizure, or persistent coma, extracorporeal removal by haemodialysis or haemofiltration may be considered, although there are no controlled trials that demonstrate an improvement in outcome with these measures [8890]
If adenomyosis is also present, endometrial ablation may fail to relieve symptoms and can sometimes lead to persistent or worsening period pain
Additional metabolic endpoints include NAD + /NADH, lactate/pyruvate, and MCT1/2/4 [10, 13,14,15,16]
as an example, a concentration of 150 pmol/l on one day may be 120 pmol/l on another day
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