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(2023) created a three-dimensional vascularized hepatocellular carcinoma chip composed of various cell types, which can simulate liver hardness under normal or cirrhosis conditions and provides a powerful tool for studying the tumor microenvironment and how drug delivery methods can adjust the chemotherapy resistance of hepatocellular carcinoma

Figure 1 2.7 Calculations and statistics All data were statistically analyzed using the MIXED procedure of SAS version 9.4 (SAS Institute Inc., Cary, North Carolina, USA) with the restricted maximum likelihood method

c-d , For example, we took the growth media from wild-type cells, just before growth at 39.2 O C ( c ) or during late log-phase growth at 30.0 O C ( d )

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