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The 2-year STEP 5 study discussed here aimed to assess the sustained impact of weekly subcutaneous semaglutide 2.4 mg, in conjunction with behavioral interventions, on body weight and cardiometabolic risks among non-diabetic adults grappling with obesity (BMI 30 kg m2) or overweight (BMI 27 kg m2 with at least one related comorbidity)
10.1007/s10048-025-00821-y 46
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12 Preserving or even building muscle through strength training helps keep the metabolism elevated, supporting both initial weight loss and, crucially, long-term weight maintenance
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