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While there can be a number of mostly gastro-intestinal side-effects from Tirzepatide and others (acid reflux, burping, constipation, nausea) by starting at a really low dose, increasing slowly and not going too high on the dose most of these types of side-effects can be minimized
This bypasses the gastrointestinal tract, which can be beneficial as it avoids the first-pass metabolism in the liver, potentially increasing the bioavailability of glutathione
GLP-1 medications are powerful tools, but they are not thyroid treatments
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