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The patients treated with tirzepatide showed significantly lowered systolic and diastolic BP compared with patients in the control group, regardless of whether tirzepatide was used as a monotherapy or add-on therapy
To thoroughly assess any potential side effects associated with MT-II, such as changes in weight or general behavior, normal C57BL/6J mice underwent a longer, fourteen-day continuous ICV administration of MT-II at the same daily dose
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