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This early failure curve is consistent with tachyphylaxis, a reduced drug response after prolonged exposure
Par prcaution, lutilisation du glutathion est dconseille pendant la grossesse et lallaitement sans avis mdical
Acknowledgements This work was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI (Grant Numbers JP20H05626 (H.S.), JP25H00970 (H.S.), JP23H02076 (F.N.), JP24K01641 (K.O.), JP23KJ1331 (E.M.)), the Japan Science and Technology Agency (JST) CREST (Grant Number JPMJCR23B3 (H.S.)), JST FOREST program (Grant Number JPMJFR2002 (K.O.)), iPS Cell Research Fund from Centre for iPS Cell Research and Application (Kyoto University)
Distinct clinical and pathological features are associated with the BRAF(T1799A(V600E)) mutation in primary melanoma
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