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In cell studies, folate deficiency upregulates miR-22 and miR-149
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Ideal candidates include patients with acute sports injuries seeking accelerated recovery, chronic tendinopathies that have not responded to conservative management, post-surgical orthopedic cases where optimized healing is a priority, inflammatory joint conditions where traditional treatments have fallen short, and autoimmune-mediated pain where immune modulation may provide benefit
Its proposed roles in tissue repair, anti-inflammatory modulation, hair growth promotion, neuroprotection, and gene expression modulation present exciting avenues for future investigations
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