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Regulation of human epidermal melanocyte biology by beta-endorphin.The Journal of Investigative Dermatology
In addition to the classical PD-1/PD-L1 pathway, the T-cell immunoreceptor with Ig and ITIM domains (TIGIT)/CD155 axis has recently emerged as a critical mediator of immune evasion in osteosarcoma
Bulletin of Experimental Biology and Medicine , 135(6), 590592
The increase in cAMP activates downstream signaling cascades, primarily through protein kinase A (PKA), and upregulates the expression of melanogenic enzymes, resulting in increased eumelanin synthesis and visible skin darkening (Figure 4)
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