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The closed conformation of the peptide-free GLP-1R compared to GCGR is quite divergent in the extracellular region and may be a consequence of sequence diversity, which is important for understanding the signalling pathway for different receptors within the class B family
Some individuals report changes within days or weeks, while others may require a longer period of treatment
This reduced rate of death in culture resulted in extended survival (up to 40 days) of rat sensory neurons in primary culture [15]
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