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However, traditional treatments, such as oral drugs, have limitations in effectively addressing digestive system diseases
In prostate cancer, emodin treatment causes necroptosis-mediated cell death by stimulating the expression of HSP90 and PGAM5, a central modulator of mitochondrial fission, leading to the massive generation of ROS and necroptosis (Zhou et al., 2023)
NRF2, A transcription factor for stress response and beyond
More concerning is the potential for vitamin toxicity from excessive doses
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