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The drug was known to lower blood sugar and promote weight loss, but patients livers were improving in ways that those effects alone could not explain
Its mechanism of action involves: master antioxidant that neutralizes free radicals, inhibits tyrosinase enzyme for melanin reduction, and supports detoxification pathways
This selection may also have influenced the observed adverse event rates, as treatment tolerability and physician familiarity with specific agents may have varied over time, potentially affecting both reporting and management of side effects
doi: 10.1159/000506879CrossRefGoogle ScholarPubMed Chanson, P., Arnoux, A., Mavromati, M., Brailly-Tabard, S., Massart, C., Young, & J., for the VARIETE Investigators (2016)
