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However, additional studies would be necessary to validate these conclusions
Yet, more recently, a metabolomic analysis reveals the importance of glutamine uptake by ASCT2 and its conversion into ROS-producing intermediate metabolite -Ketoglutarate as marker of sensitivity during sulfasalazine xCT-inhibition cell death in head and neck squamous cells carcinoma (46)
Am J Transl Res (2019) 11(8):465066
This difference became even more pronounced when comparing TCC-treated wounds to control wounds on days 7, 14, and 21, where the TCC group consistently showed significantly smaller unhealed areas
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