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They're based on glycemic effects, not weight loss effects
It is intriguing to see that cellular metabolism and immune activation are so tightly entangled and that a fine-grained interplay is essential to achieve a correct function, said Karsten Hiller, Ph.D., a co-author of the current study and a professor at the Braunschweig University of Technology
(2) GLP-1RAs can also induce Tregs and microglia to secrete IL-10, which further promote microglia to secrete chemokines (Ccl2, Ccl7, and Cxcl10) and IGF-1
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