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This is also the structure Novo Nordisk's own investigational semaglutide+cagrilintide combination used in REDEFINE 1 (Garvey et al., NEJM 2025) both components stepped in parallel through a 16-week ramp rather than introduced together at maintenance
Lift it away from the underlying muscle
Human clinical data is limited
The peptide anxiolytic properties, mediated through GABA and serotonin pathways, are also relevant since anxiety and mood disorders are common comorbidities in MS that significantly impact quality of life
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