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GLP-1-RA such as liraglutide [4], semaglutide [5], and the dual agonist tirzepatide [6], activating both the GLP1- and the gastric-inhibitory polypeptide receptor (GIP-R), have been shown to significantly reduce body weight, making them a promising therapeutic option for the treatment of obesity
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Klinischer Status: Beide Peptide wurden in frhen klinischen Studien am Menschen zur Behandlung von Wachstumshormonmangel und zur Stoffwechselforschung untersucht
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