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Pharmacological Reviews 68 (4): 954-1013

Alternative hypotheses are provided by El-Ansary, Bhat, and Zayad [134], who speculate that higher ASD phenotypes in males compared with females could be attributed to the protective effect of estrogen, the higher diversity and predominance of probiotics in females, and the lower liability of females to develop leaky gut, neuroinflammation, and excitotoxicity

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Indeed, there is growing interest in the potential of new classes of anti-diabetic medications such as glucagon-like peptide-1 receptor (GLP-1R) agonists and sodium-glucose cotransporter 2 (SGLT2) inhibitors, to reduce the risk of cardiovascular events and slow down the progression of neuronal damage