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Adults randomly assigned to receive tirzepatide had a mean weight loss of 16% with 5 mg, 21.4% with 10 mg, and 22.5% with 15 mg compared with a 2.4% mean weight loss for those assigned placebo
Key considerations for oral formulations: Convenient: Familiar to most patients and easily integrated into daily routines without clinic visits
Animal models of heart failure: a scientific statement from the American Heart Association
These limitations included reliance on electronic health record data, the possibility of underreporting for adverse events relative to protocoled, prospective trials, and reliance on brand as a proxy for target dose, among others
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