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How to evaluate the risk of the S-EDCs
In the earliest stage of development, junctional nests of melanocytes appear in the lower aspect of the epidermis (confined by the basement membrane), usually within the tips or, less often, sides of sometimes broadened and elongated epidermal ridges (lentiginous junctional nevus) (Figs 25.36, 25.37)
These molecules cause "oxidative stress," which is essentially biological rust
However, both medications can affect appetite, cardiovascular parameters, and gastrointestinal function in overlapping ways that require medical monitoring
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