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For the single-receptor comparison, STEP studied semaglutide for weight management (NEJM 2021)
As of early 2025 the FDA had logged more than 320 adverse-event reports tied to compounded tirzepatide
In clinical studies, the medication showed an average weight reduction of 3-9% of body weight
This is normal in nutrition research and worth knowing, especially when both positive and null trials exist on the same strain
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