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Diterpenoid alkaloids isolated from Delphinium brunonianum and their inhibitory effects on hepatocytes lipid accumulation
The antiproliferative effect of calcitriol involves multiple pathways, such as the expression of cyclin-dependent kinase inhibitors (i.e., CDKN1A and CDKN1B), the production of growth factors (i.e., TGF-, IGF) and miRNAs, the regulation of cancer stem cell proliferation, tumor angiogenesis, epithelial-mesenchymal transition, and the activation of caspases (49, 5356)
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Furthermore, semaglutide treatment led to an increase in mitochondrial content and density, as well as an increase in maximal mitochondrial respiration
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