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Analysis of the mice' bone marrow cells, precursors of the monocytes, showed upregulation of proinflammatory cathepsin protein family (CatB and CatZ), which was later terminated during bone marrow differentiation to the macrophages
Adding 3 mL to a 20 mg vial gives 6,667 mcg/mL, while 5 mL produces 4,000 mcg/mL
If you do the program for 6 months and it hasnt worked, you get your money back
In contrast, systems such as microfluidic-assembled nanocapsules or electrosprayed powders remain below TRL 5 due to cost, complexity, or scalability constraints (194, 195)
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