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Mechanistically, copper delivery to HIF-1 (hypoxia-inducible factor) stabilisation may contribute copper is required for HIF-1 prolyl hydroxylase activity regulation
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Consistent with that, chromogranin A is more commonly found in epithelial mucinous tumors compared to nonmucinous tumors [217]
Copper delivery: GHK-Cu carries bioavailable copper into tissues where it can support enzymes involved in collagen cross-linking and repair
