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In contrast, Melanotan 1 mainly affects pigmentation because it works strongly through MC1R, the receptor that controls melanin production

10.1016/j.exger.2010.07.002 Summary Keywords intermittent fasting, caloric restriction, cardiovascular disease, mitochondrial function, endothelial dysfunction Citation Savencu CE, Lina A, Farca G, Bn AM, Creu OM, Malia DC, Muntean DM and Sturza A (2021) Impact of Dietary Restriction Regimens on Mitochondria, Heart, and Endothelial Function: A Brief Overview

Under ordinary circumstances, its not especially contentious when drugs come off a shortage list