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Injection site reactions (erythema, pruritus, swelling) occur in 1.4-2.4% of patients using subcutaneous formulations and are well-documented, localized effects
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In our Texas clinics, patients on the full titration schedule (starting at 2.5 mg and working up to 10 to 15 mg over several months) tend to see the best weekly averages when they stay consistent with their protein intake and injection schedule
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