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Retatrutide and tirzepatide are often compared because they represent the next wave of metabolic medications, but theyre not equally accessible

Best for Radiance : La Roche-Posay Mela B3 Serum Why We Love It: As with all products from the French pharmacy mainstay, La Roche-Posay infuses this serum with its signature thermal spring water to help soothe skin

Its made naturally in the body (synthesized in the mitochondria, where it helps enzymes turn nutrients into energy), but humans only produce ALA in small amounts, so turning to ALA-rich foods or supplements may help to optimize your intake