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All injectable dosing protocols are extrapolations from the oral trial, animal data, and clinical practice experience
If a protocol adds frequency or increases dose without a clear reason, the study may stop testing a clean pulse-based design and start testing accumulation of procedural stress
One study found that people regained about two-thirds of the weight they lost within a year of stopping semaglutide
FDA-approved for type 2 diabetes and for reducing the risk of major adverse cardiovascular events in certain adults with type 2 diabetes and established cardiovascular disease
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