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Pyroxidine is known to reduce the effectiveness of altretamine, especially when combined with cisplatin

18 Table 4 Time to Improvement of Abnormalities in Vitamin B12 Deficiency After Initiation of Treatment A 2005 Cochrane review involving 108 patients with vitamin B 12 deficiency found that high-dose oral replacement (1 mg to 2 mg per day) was as effective as parenteral administration for correcting anemia and neurologic symptoms

You may experience severe side effects like: Confusion Dizziness Extreme tiredness Dermatological Effects Most skin reactions from a B12 injection come from an allergic reaction

When this process is hindered, it can feel like your body is running on empty