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Oral and injectable options differ in bioavailability, dosing frequency, and patient conveniencefactors that influence both cost and long-term adherence
Diabetes Vasc Dis Res (2016) 13:5668
First, although the experimental data are conflicting [90], it is possible that potentiation of SDF-1 by DPP-4 inhibitors may enhance the inflammatory and proliferative responses to kidney injury and may thereby aggravate the course of diabetic nephropathy [27, 28]
However, the data suggests that the peptide does not appear to significantly influence the frequency of these growth hormone pulses or the maximum levels of growth hormone reached during each pulse
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