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The pathogenesis of sarcopenia is complex and multifaceted: the chronic catabolic condition, increased energy expenditure, reduced appetite, side effects of multiple therapies, alterations in circulating levels of hormones, low protein synthesis, and the presence of ascites or portosystemic shunts are all factors contributing to muscle atrophy in cirrhotic patients [23]
A single astrocyte domain can encompass approximately two million synapses, with their interaction potential further enhanced with gap junctions
Its mechanism of action revolves around modulating key pathways involved in inflammation, angiogenesis (the formation of new blood vessels), and collagen production
doi: 10.1016/j.jff.2020.104172 421 DengHLiuJXiaoYWuJLJiaoR
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