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Comfortable with her current weight, Kirtley is about to switch to the Wegovy pill, which was recently rolled out in pharmacies
TMAO can change the bile acid spectrum to accelerate the formation of aortic lesions in ApoE / mice, and further activate the nuclear receptors farnesoid-X-receptor (FXR) and small heterodimer partner (SHP), to reduce the expression of cholesterol 7-hydroxylase (Cyp7a1) to inhibit bile acid synthesis, thus accelerating the formation of atherosclerosis (82)
A., Tewksbury, C., Apovian, C
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