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Taken together, the pattern suggests that a controlled, short-lived immune activation may accompany epithelial repair, consistent with the accelerated wound closure observed in HCEpiC assays under basal, inflammatory and oxidative stress conditions ( Importantly, the interpretation of increased Th1-associated cytokines as part of a repair-associated response rather than purely deleterious inflammation is supported by emerging evidence on corneal wound healing biology ( It is also worth mentioning that cellular redox homeostasis could influence cellular pathways influencing cell fate and differentiation ( Among the strengths of the present study, the prospective, double-blind, two-period crossover design enabled within-subject assessment of clinical outcomes and tear-fluid cytokines, minimizing inter-individual variability and improving efficiency to detect reversible changes
Descriptive statistics were used to summarize participant characteristics, including counts and percentages for categorical variables and means (SD) for continuous variables
La forme active de glutathion correspond la forme rduite (GSH) , capable de neutraliser les radicaux libres lintrieur des cellules
Treg cells rely on the GPX4 pathway to resist cellular ferroptosis to maintain normal mitochondrial homeostasis and the expression of inflammatory factors such as IL-1 [72]
