These include: Nausea (very common), typically most pronounced in the first few weeks Vomiting and diarrhoea (common), which can contribute to dehydration Constipation (common), which may require dietary adjustments Abdominal pain and bloating (common), related to delayed gastric emptying Reduced appetite (very common), which whilst therapeutically beneficial for weight loss, may lead to inadequate nutrition if extreme These effects usually diminish over time as tolerance develops
Nat Immunol (2008) 9:45961.10.1038/ni0508-459 32 BryanHKOlayanjuAGoldringCEParkBK
"One way to know which foods affect you in this way is to use a continuous glucose monitor and look at what a certain food or combination of foods does to your blood glucose level within 30 minutes." Limit Highly Processed, Sugary Foods Foods and drinks that are high in added sugar - such as candy, pastries, soda, and other sweetened beverages - can cause rapid blood sugar spikes and offer little nutritional value
Type 2 diabetes models: Because the peptide affects blood-sugar signaling, researchers also look at it in metabolic and diabetes-related research