Bottom line: side effects live next to dose day, food, and weight, so a rough day reads as part of the week instead of a symptom in isolation
GLP-1 (glucagon-like peptide-1) is a naturally occurring incretin hormone secreted by enteroendocrine L-cells in the small intestine in response to food intake, where it signals satiety to the brain through hypothalamic receptor binding, slows gastric emptying to prolong the feeling of fullness, and modulates the release of insulin and glucagon in a glucose-dependent manner that helps stabilize post-meal blood sugar without the hypoglycemia risk associated with older drug classes
Across public platforms, complaints most often relate to delayed pricing visibility, intake-linked billing, portal-only support, and pharmacy steps that are not explained in advance
Both cause similar GI side effects: nausea, vomiting, diarrhea, constipation