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To determine internal validity, occurrence of diabetic nephropathy and change of estimated glomerular filtration rate (eGFR) were considered positive control outcomes because of the evidence of renoprotective effects of SGLT2is [23]

Global activation of CD8 + cytotoxic T lymphocytes correlates with an impairment in regulatory T cells in patients with generalized vitiligo

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Importantly, as there has been discussion in the media about possible adverse effects of the drugs on mental health, the group taking the drug had a lower incidence of schizophrenia, alcohol and drug use disorders, and less suicidal ideation