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These components act as vigilant cellular guardians, protecting against damage caused by free radicals
Without adequate antioxidant protection, these radicals can damage proteins, DNA, and cellular membranes
A plausible explanation could be a reorientation of Lys105 towards GS resulting in a decreased stabilization of the active site thiolate as a leaving group
Tumor risk via p53 pathway interference Mitigate risk by: Careful patient selection: exclude patients with pre-existing active malignancy or high tumour risk (e.g., known p53 mutations, familial cancer syndromes)
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