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Limitations of both the analysis reported here and previous meta-analyses are that the trials they include were not specifically designed to address these research questions, and that the trials included subjects at high risk of a CV event and, as such, may not be representative of the broader type 2 diabetes population
Casciani CU, Caruso U, Cravotto E, and et al
This pattern reflects how GLP-1 receptor agonists work: they suppress appetite and slow digestion while you take them, but weight-loss benefits typically diminish once treatment stops
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