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Among these, BRAF V600E is the most prevalent mutation, ranging from 25% to 82% [70]
Before starting a GLP-1 or GLP-1/GIP medication, you should ask whether your thyroid disease is stable, whether you have any personal or family history of medullary thyroid carcinoma or MEN2, and when your next thyroid labs should be checked
According to NICE guidance (NG28), these medications have demonstrated significant benefits in glycaemic control, with some specific agents (semaglutide, liraglutide, dulaglutide) also showing cardiovascular risk reduction in clinical trials
JAMA 290:486494 Segal P, Eliahou HE, Petzinna D et al (2005) Long-term efficacy and tolerability of acarbose treatment in patients with type 2 diabetes mellitus
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