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Exposure to pro-oxidant stimuli usually induces Nrf2 activation and upregulation of antioxidant enzyme expression through binding to the antioxidant response element (ARE), localized in the antioxidant enzyme gene promoters

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[sources 18] subjective responses to amphetamine appear to correlate positively with plasma or salivary estrogen concentrations

Most hepatic benefits correlate with the degree of weight loss achieved rather than direct liver receptor effects