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Animal care and use All experiments involving animals were conducted in strict accordance with the recommendations in the Guidelines for Proper Conduct of Animal Experiments published by the Science Council of Japan and ethics approvals from the Kyushu University Institutional Review Board (approval No

Chronic daily administration of cotadutide over 27 days in obese mice was associated with food intake reduction, decreased adiposity, improved fasting glucose, and increased energy expenditure

Doing so can increase the risk of side effects, such as nausea, digestive discomfort, or, in rare cases, pancreatitis, without providing extra benefit