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Neuron 43(4):527537
Many studies were small, used different dosing methods, and do not provide the kind of large-scale evidence used to support standard insomnia treatments
Dose reduction to 10 mg daily should be considered if side effects occur, with the most common reported side effects being diarrhea, nausea, headache, rash, itching, loss of hair and body weight, hypertension, chest pain, palpitation, infection, and liver failure
Interestingly, shGSTM2-HepG2 cells contained more LDs (~5 to 6 fold) in normal culture than shNC-HepG2 cells (Fig
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