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Excess body fat produces small amounts of estrogen, which can influence hormonal balance but does not create major hormonal fluctuations
Mounting evidence suggests that GLP-1 RAs have benefits beyond reducing blood glucose that include improving kidney function in people living with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), a common microvascular complication of T2DM
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Therefore, GIP might increase metabolic flexibility by enabling increased fat utilisation in the fasting state and reducing fat availability in the postprandial state [24 25]
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