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L.LemastersJ
Other sources of superoxide can be enzymatic reactions that transfer electrons to the ETC such as mitochondrial glycerol 3-phosphate dehydrogenase (mGPDH), and the last step of -oxidation, electron-trasferring flavoprotein ubiquinone oxidoreductase (ETFQOR) or dehydrogenases such as pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxoacid dehydrogenase (BCKDH)
CB: Writing original draft, Data curation
Patients considering discontinuation should engage in thorough discussions with their healthcare providers about realistic expectations and alternative management strategies, with follow-up monitoring within 4-12 weeks after any treatment change
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