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We investigated two common TYMS polymorphisms in 94 MDS and 113 control mothers of Italian origin (Copped et al., 2009), namely a 28-bp short tandem repeats (rs34743033) in the 5-untranslated region (5-UTR) that is linked to gene expression levels (Horie et al., 1995), and a 6-bp deletion (1494 ins/del) polymorphism in the 3-UTR (rs34489327) that affects mRNA stability into the cytoplasm (Ulrich et al., 2002)
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10.1371/journal.pone.0263149 PLoS One
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