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CNS Drugs 27, 493503
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Semaglutide is a medication that mimics the effects of a hormone called glucagon-like peptide-1 (GLP-1), which is produced naturally in the body to regulate appetite and blood sugar levels
Other gut hormone-based drugs have recently been introduced to the clinic or are still under clinical development and promise to be even more effective than semaglutide, such as the dual GLP-1R and glucose-dependent insulinotropic peptide receptor (GIPR) agonist tirzepatide [4] and the triple GLP-1R, GIPR, and glucagon receptor (GR) agonist retatrutide [5]
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