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A positive effect was observed in 20% of the patients, in whom tumor regression or stabilization correlated with decreased Tg plasma level or increased iodine uptake

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[15] In the mice with cardiac-specific overexpression of Trx1, the proteomics study found that SET and MYND domain-containing protein 1 (SMYD1), a lysine methyltransferase highly expressed in cardiac and other muscle tissues, is also upregulated