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Knockdown of GLS2 but not GLS1 can inhibit cysteine starvation-mediated ferroptosis of MEFs [86]
Redox balance in melanocytes ROS in melanocytes ROS, which include both free radicals and their non-radical intermediates, are produced primarily by mitochondria and peroxisomes during normal cellular metabolic processes or because of exogenous prooxidant exposure 42 (Fig
10.3181/0812-RM-364 23
Obesity-related comorbidities also lead to a substantial increase in US medical costs, with annual costs being $2505 higher among adults with obesity compared with those with normal weight, which totals to an estimated $260.6 billion in aggregated costs [3]
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